Three‐phase bio‐nanocomposite natural‐rubber‐based microfibers reinforced with cellulose nanowhiskers and <scp>45S5</scp> bioglass obtained by solution blow spinning

Abstract Aiming at biomedical applications, the present work developed a new bio‐nanocomposite fibrous mat based on natural rubber (NR) reinforced with 45S5 bioglass particles (BG) and cellulose nanowhiskers (CNW), which reveals excellent mechanical properties, good biocompatibility bioactivity properties. Analyses of specimens were conducted by means morphological observations (SEM) thermal analysis (TG/DTG), as well tests used to verify effect incorporation BG CNW ultimate properties these flexible NR‐CWN/BG membranes. An SEM revealed that all filaments possessed ribbon‐like morphology, increasing diameters concentration increased. This likely results from an increased viscosity solution for fiber blowing. In comparison neat NR mats, bio‐nanocomposites significantly improved due presence dispersed in matrix. According TG/DTG analysis, specimens' stability was unaffected high content, profiles similar, isoprene chains decomposition occurring between 350 450°C. In‐vitro fibroblasts confirmed mats are noncytotoxic. It found enhanced cellular growth hold great promise tissue engineering applications.